Detalhe da pesquisa
1.
Dabrafenib plus trametinib in patients with relapsed/refractory BRAF V600E mutation-positive hairy cell leukemia.
Blood
; 141(9): 996-1006, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36108341
2.
Dabrafenib plus trametinib in patients with BRAFV600E-mutant low-grade and high-grade glioma (ROAR): a multicentre, open-label, single-arm, phase 2, basket trial.
Lancet Oncol
; 23(1): 53-64, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34838156
3.
Dabrafenib plus trametinib in patients with BRAFV600E-mutated biliary tract cancer (ROAR): a phase 2, open-label, single-arm, multicentre basket trial.
Lancet Oncol
; 21(9): 1234-1243, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32818466
4.
ROAR trial: which treatment is effective after progression? - Authors' reply.
Lancet Oncol
; 23(3): e94, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35240095
5.
Dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: the phase 2 ROAR trial.
Nat Med
; 29(5): 1103-1112, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059834
6.
Comparative Bioavailability of a Single Dose of Trametinib (TMT212) Containing 9% vs 11% Dimethyl Sulfoxide in Randomized Healthy Volunteers to Assess Long-Term Storage at Room Temperature.
Clin Pharmacol Drug Dev
; 11(10): 1203-1210, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35736001
7.
Pharmacokinetic Interaction Between the MEK1/MEK2 Inhibitor Trametinib and Oral Contraceptives Containing Norethindrone and Ethinyl Estradiol in Female Patients With Solid Tumors.
Clin Pharmacol Drug Dev
; 11(5): 585-596, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35157784
8.
Open-label, phase IIa study of dabrafenib plus trametinib in East Asian patients with advanced BRAF V600-mutant cutaneous melanoma.
Eur J Cancer
; 135: 31-38, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32534242
9.
P(RNCH(2)CH(2))(3)N: Efficient Catalysts for Transesterifications, Acylations, and Deacylations.
J Org Chem
; 64(9): 3086-3089, 1999 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-11674405
10.
P(RNCH(2)CH(2))(3)N: efficient 1,4-addition catalysts.
J Org Chem
; 67(11): 3555-60, 2002 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-12027665
11.
Trapping HIV-1 reverse transcriptase before and after translocation on DNA.
J Biol Chem
; 278(18): 16280-8, 2003 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12554739
12.
Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA.
EMBO J
; 21(23): 6614-24, 2002 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12456667